Walk Through

In this section we discuss how to regenerate results from an analysis from scratch. Each step consists in a separate workflow for which a dedicated documentation is referenced. While workflows are platform agnostic, due to complex data permissions and governance, each workflow is typically run on a dedicated platform.

Step 1: Aggregating Genetic Datasets

• workflow: Combining GenOMICC Datasets
• platform: ODAP

Step 2: Imputation of Genotypes

• workflow: TOPMed Imputation
• platform: Eddie

Step 3: Merging GenOMICC and the UK Biobank

• workflow: Merging the GenOMICC and UK Biobank Cohorts
• platform: UKB RAP

Step 4: GWAS

• workflow: WDL-GWAS
• platform: UKB RAP